Manchester United left-back Sergio Reguilon will miss out for a fourth consecutive match with a hamstring problem.
Winger Antony, who made his first appearance for a month as a substitute in midweek, could start.
Brentford’s injury list shows no sign of clearing up, with sidelined players including Rico Henry and Josh Dasilva.
Ben Mee, who has a muscle injury, is the closest to a return, but will not be fit in time for this weekend.
MATCH FACTS
Head-to-head
- Manchester United have won three of the four Premier League meetings, losing the other 4-0.
- Brentford have lost their five most recent away games against United in all competitions, last winning there in February 1937.
- The Bees are yet to score at Old Trafford in the Premier League.
Manchester United
- Manchester United have been beaten in five of their past seven games in all competitions. They have lost six of their opening 10 matches in a season for the first time in 37 years.
- United could lose at least five of their opening eight league fixtures in a season for the first time since 1986, which happened weeks before Sir Alex Ferguson was appointed.
- They are in danger of suffering three home league defeats in a row for the first time since February 1977.
- Erik ten Hag’s side have conceded first in each of their past three home league games.
- They have used 25 players in the Premier League in 2023-24, a joint high with Sheffield United.
Brentford
- Brentford are winless in five Premier League matches (D3, L2).
- They have dropped a joint division-high eight points from winning positions this season.
- The Bees have gone six top-flight away games without a win (D2, L4) but are unbeaten in each of their past six away league London derbies.
- Neal Maupay has failed to score in any of his past 29 Premier League appearances.
